Pregnancy of unknown location

We are currently reviewing this course in line with recent changes to Special Interest Training and the launch of the new Obstetrics and Gynaecology Curriculum 2024. As such, please be aware that the accuracy of the existing content cannot be guaranteed. Further announcements will be added here over the coming months.

Welcome to this Special Interest Training course on Pregnancy of unknown location (PUL).

When you have completed this course, you will be able to:

• define PUL and its subsequent pregnancy outcomes
• assess women with PUL, including any risk factors for ectopic and the atypical/non-gynaecological signs and symptoms
• interpret various investigations including transvaginal ultrasound scans, serum β-hCG levels, serum progesterone levels, serial β-hCG ratios and mathematical models in the investigation of PULs
• manage various outcomes/definitive diagnoses of PUL including ectopic pregnancy, intrauterine pregnancy or miscarriage and ‘persistent PUL’, understanding how to balance safety and intervention in the different management options
• recognise current strategies in management options of ectopic pregnancies, including expectant, medical and surgical, their indications, success rates, follow-up and future fertility including details e.g. salpingostomy versus salpingectomy
• management options for the rarer non-tubal ectopic pregnancies – conservative, minimally invasive and surgical options; their risks, complications, follow-up and associated future fertility
• gain information about the most up-to-date relevant published evidence.