The management of primary rubella, symptomatic and asymptomatic rubella reinfection depends on the point in gestation in which rubella occurred, and the individual circumstances of the women.
Due to the low, but definite, risk to the fetus of maternal rubella reinfection in the first 16 weeks of pregnancy, there may be circumstances when further fetal investigation by genome detection is carried out, to ascertain if fetal infection has occurred. A range of possible approaches has been explored, but they are all invasive, e.g. amniocentesis and fetal blood sampling. They, therefore, carry a risk of an adverse outcome. The necessary virological techniques for fetal investigation are not validated and available in the UK, and it is strongly recommended that management be based on risk assessment.