In August 2021, the RCOG published version 14 of the guidance Coronavirus (COVID-19) Infection in Pregnancy, to include the latest data on vacciantion. The guideline summarises the results of a breadth of global trials regarding the safety of the four UK-approved vaccines for COVID-19 in pregnant and breastfeeding women. The guidance advises that all pregnant and breastfeeding women should be offered the COVID-19 vaccine at the same time as non-pregnant women – in accordence with their age and risk of complication from infection – as there are no data to suggest adverse effects on the fetus or breastfed baby.
In the UK, pregnant women should be offered the Pfizer-BioNTech or Moderna vaccines unless they have already had one dose of the Oxford-AstraZeneca vaccine, in which case they should complete the course with Oxford-AstraZeneca. This is to mitigate against the minimal risk of vaccine-induced thrombosis and thrombocytopenia associated with the Oxford-AstraZeneca and Janssen vaccines.