The word ‘sepsis’ describes a toxic condition resulting from the generalised spread of bacteria or their toxins from a localised infection.This section will look at:puerperal sepsis (genital tract sepsis)septic shockneonatal sepsis at birthchorioamnionitis.Royal College of Obstetricians and Gynaecologists. Bacterial Sepsis in Pregnancy. Green-top Guideline 64a. London: RCOG Press. 2012.Royal College of Obstetricians and Gynaecologists. The Prevention of Early-onset Neonatal Group B Streptococcal Disease. Green-top Guideline 36. London: RCOG Press. 2012.Acosta CD, Harrison DA, Rowan K, Lucas DN, Kurinczuk JJ, Knight M. Maternal morbidity and mortality from severe sepsis: a national cohort study. BMJ Open 2016;6:e012323. Zwart JJ, Richters JM, Öry F, de Vries JIP, Bloemenkamp KWM, van Roosmalen J. Severe maternal morbidity during pregnancy, delivery and puerperium in the Netherlands: a nationwide population-based study of 371 000 pregnancies. BJOG 2008;115:842–50.